HL-SAN

This enzyme will allow for removal of nucleic acids in a traditional protein buffer regime – ie the protein is well protected while the nucleic acids are fully removed. Digests DNA and RNA in approximately a 10:1 ratio. Applications in removal of contaminating nucleic acids from purified enzyme/protein preps as well as inline digestion of nucleic acids in protein purifications. The digestion can take place at high salt conditions.

Main advantages with Salt Active Nuclease

• Non specific endonuclease
• Optimum activity at high salt concentration (0.5 M NaCl)
• Active at low temperatures (20% at 6ºC)
• Broad pH range
• Temperature stable

• Complete removal of DNA
• Viscosity reduction

Publications

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